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ID : tm3149012461


Xanthine Oxidase Inhibitors From Blumea Balsamifera DC: Molecular Basis

The leaves of Blumea balsamifera DC (Sembong) are traditionally used in conditions related to urolithiasis or kidney stone. The most common kidney stone is the calcium oxalate stone, however uric acid stones can be formed as a mixture of uric acid and calcium oxalate stones. Uric acid production is catalyzed by xanthine oxidase(XO). This enzyme damage of living tissues. Phytochemical investigation on the Blumea balsmifera leaves' extract resulted in the isolation of hydrocarbons, phytosterols and flavonoids. In this study, the inhibition of xanthine oxidase activity by the flavonoids was assessed.

Minden Pulau Pinang

ID : tm3149112462


Wb rapid - An Immunochromatography test for the rapid and accurate detection of Wuchereria bancrofti filaria infection

Lymphatic filariasis caused by Wuchereria bancrofti affects more than 100 million people in 80 countries. This mosquito-transmitted disease results in symptoms that include fever, lymphatic & renal damage, adenolymphangitis, hydrocoele, chyluria, lymphoedema and elephantiasis. Wb rapid is an immunochromatography-based rapid test for the detection of specific lgG to W. bancrofti. It employs BmSXP recombinant antigen which is immobilized on a membrane strip. If specific antibodies are present in the test sample (serum/plasma/blood), it forms an antibody-antigen complex with the immobilized antigen; and subsequently detection by a dye conjugated anti-human lgG, giving a pink-purplish coloured line/band. The control line contains goat anti-mouse lgG-dye conjugate, and serves as an indication of proper migration plus reagent control. The test demonstrated sensivity of 95-100% and specificity of 99-100%.

Minden Pulau Pinang

ID : tm3149212463


Wb Rapid - An Immunochromatographic Assey For The Detection Of Specific IgG4 To Wucheria Brancofti

An Immunochromatography test for the rapid and accurate detection of Wuchereria bancrofti filaria infection. WB Rapid is a good diagnostic tool for the Global Program for Elimination of Lymphatic Filariasis and Patient diagnosis and follow-up post-treatment.

Minden Pulau Pinang

ID : tm3149312464


Waste to Wealth: A New Composite

Awareness towards enviromental impact had stimulated the interest for converting polystyrene from waste materials into value added-products so called from 'waste to wealth'. Recycling is one of the common and easy process for waste management. However, polystyrene foams have recycling limitations because it contains flame retardant material. In this invention, we overcome this problem by using a new technique of recycling whereby converting the waste polystyrene to a new resin. After extensive studies, the new resin applied as matrix material reinforces with oil palm empty fruit bunch (EFB) fiber to produce new composite materials. Excellent adhesion between the polystyrene resin and the EFB fiber had exhibit promising results on tensile, flexural and impact properties. In addition, the new composite materials are low weight, low water uptake and customizable as can be applied in furniture.

Minden Pulau Pinang

ID : tm3149412465


WALLPro: A Load Reducing Geocomposite for Retaining Structures

In 2003, the ministry of Transport Malaysia's record indicated more than eleven milion registered vehicles in malaysia. Recent statistics for malaysia indicated more tahan 100% increases in number of registered vehicle within twn years. An average total of more than 5 million scrap tires are produced every year since 1987. At an average of 20kg for each tire, this would come up to 100,000 tonnes a year. The trend iis increasing with increasing populations and number of vehicles.

Minden Pulau Pinang

ID : tm3149512466


ViscoLigno: A 4-in-1 solution for drillers

The formulation of drilling mud is one of the most important aspects in drilling engineering. This is because the drilling muds are capable of lubricating and cooling the drill bit and drill string as well as carrying cuttings out of the borehole. All of these funtions require appropriate viscosity of drilling muds to facilitate pumping, circulate the cuttings and transfer them to the surface. Apart from that, adequate gelling property (gel strength) of the drilling muds is also required to prevent drill cuttings from settling down at the bit. Noteworthy, some of the chemicals or additives commonly used as a drilling mud gelling and viscosifying agents are carboxymethyl cellulose (CMC), xanthane and guar gum. However, these commercial drilling additives are subjected to thermal and biological degradation at temperature above approximately 120C. ViscoLigno has been formulated from oil palm lignocellulosic waste to overcome the obove shortcoming especially for deeper hydrocarbon wells. The rheological performances of the product as a drilling mud multi-functional agent showed that, ViscoLigno gave good gelling and viscocity building abilities at low dosage of 0.5 % w/w. ViscoLigno also can stand high temperature (200C which is equivalents to about 10 km depth) as a drilling mud gelling and viscosifying agent without the addition of other chemical. Moreover, this product capable of maintaining the pH of drilling mud at desired pH range of 8-10 at various temperatures without the use of pH controls agents; and not to mention that ViscoLigno is also able to act as a corrosion retardant agent for drill string and subsurface drilling equipments. These will definitely minimize the use of extra chemical while drilling, which will directly reduce the enviromental risk and at the same time reduce the cost of drilling operations.

Minden Pulau Pinang

ID : tm3149612467


ViscoLigno : Drilling mud additive powder

ViscoLigno is a new drilling mud additive that was developed from oil palm lignocellulosic waste. ViscoLigno is formulated for drilling in the oil and gas industry. It is environmentally friendly and can withstand extreme conditions in deep oil well.
Compared to other conventional drilling mud chemical additives, ViscoLigno has the following advantages:
- good gelling and viscosity building abilities.
- can withstand high temperature (200 C).
- can maintain the pH level of drilling mud at the desired
level (8 to 10) at various temperatures.
- able to act as a corrosion retardant agent.
- can reduce the cost of drilling operations.
- can avoid the use of harmful chemicals that threaten the
environment.

Minden Pulau Pinang

ID : tm3149712468


Vaccine Production

Virulant strains of vibro bacteria has frequently been isolated from diseased marine fish, causing vibriosis disease. Home-made whole vaccine produced in our laboratory and some field trials indicated good protection agains vibriosis.

Minden Pulau Pinang

ID : tm3149812469


UV sensor based on Titanium dioxide (TiO)natotubes

The ultraviolet spectrum has both beneficial and damaging effects to humans. High ultraviolet (UV) intensity areas can be found in laboratories, hospitals and industries where UV instruments are used. People who are exposed to high doses of UV light are at risk due to the mutagenic effect of UV. UV sensor which is able to detect and provide fast information about leakage of UV light is an essential working tool for these people. These are various types of UV light sensors in the market. UV sensors are commonly fabricated based on semiconductor compounds such as GaP, AIGaN and SiC. The raw materials for these compounds are expensive and techniques used to grow the compounds are complicated.

Minden Pulau Pinang

ID : tm3149912470


UV B Radiation at Penang

To measure harmful solar ultra-violet radiation reaching to earth surface. To provide much needed information on the radiation level climatology at present. To monitor possible ultra-violet radiation increase due to ozone depletion. To provide feedback on harmfuleffects of UV radiation.

Minden Pulau Pinang

ID : tm3150012471


Utilization of innovative ingredient from jackfruit seed in health fibre bread.

Jackfruit seed flour resistant starch was analysed as dietary fibre by the AOAC method. Modern processing conditions in general did not affect the total dietary fibre level of jackfruit seed flour. So manufacturers and consumers would get the fibre as expected. The bread gave an outstanding eating quality in terms of colour, taste and high in fibre and virtually fat free (<1%)

Minden Pulau Pinang

ID : tm3150112472


UREX1: Food Grade High ORAC Ulam Raja Extract (Cosmos Caudatus) for Nutraceutical Applications

Fresh Ulam Raja (Cosmos Caudatus) has, for centuries, been consumed as salad with rice and sambal. Its health benefits range from anti-aging, blood cleansing and circulation, derived probably from the various antioxidative compounds found in the plant???s leaves. However, the traditional practice of eating Ulam Raja as a salad to enhance health is given less attention these days due to changed eating habits and lifestyle. Regular consumption of this health-enhancing green has become less convenient for urban consumers. UREX1 is a powdered, food-grade extract made from an optimum extraction process of Ulam Raja. The powder is water soluble and has high Oxygen Radical Antioxidant Capacity (ORAC value) of 2833 micromole trolox equivalence per gram, at par with commercial nutraceutical products in the market. An intake of foods or food products with an ORAC value of 3000-5000 micromole trolox equivalent per day is recommended to slow down aging and the onset of many chronic diseases (USA Center for Aging). UREX1 is a potential nutraceutical-antioxidant product either in capsule (~1 gram a day) or in beverage form. UREX1 may also be combined with other antioxidant-rich fruits or extracts for various commercial purposes. With UREX1, consumers will find it more convenient to enjoy the health benefits of Ulam (traditional Malays salad).

Minden Pulau Pinang

ID : tm3150212473


Unidireational link mesh network over DVB-S(Direct video broadcast - Satellite)

Existing geostationary satelite network typically are bidirectional Poin-to-Point star configuration network or Point-to-Multipoint unidirectional network for transmission. The combination of Point-to-Multipoint unidirectional technology with bidirectional transmission in the form of a Unidirectional Link (UDL) mesh is expected to improve bandwith utilization, latency and cost. A brief overview of traditional Poin-to-Point configuration vs UDL mesh links is presented. We have implemented a prototype UDL mesh network in the lab using a ULE encapsulator in bridge frame encapsulation mode. Each UDL node requires an ASI (Asynchronous Serial Interface) card connected to a DVB-S modulator and must have (N-1) DVB receiver cards where N is the number of nodes in the UDL mesh network. Transmission of data is performed through the ASI interface at a frequency allocated for a node, while each of the (N-1) DVB receiver cards on a UDL node is responsible for receiving data from the other (N-1) UDL peer nodes.

Minden Pulau Pinang

ID : tm3150312474


ULC Agro-fibre Modular Septic Tank

Malaysia's most common form of sewerage system is the invidual septic tank (IST). There are an estimated 1.2 million premise with individual septic tanks in the country. An IST comprises two chambers connected in series. In the first chamber, solids from the incoming sewage settle forming a "sludge", while greases and oils float to the surface forming a "scum" layer. Effluent from between the scum and sludge layers then passes into the second chamber where further sedimentation occurs. Presently, prefabricated ISTs are made from fibreglass, a mixture of glass fibre and unsaturated polYester. Currently the production cost is about RM800 with the price increasing with the increase in oil palm industry are produced in large quantities in Malaysia, approximately more than 10 millions tonnes per annum. Subtituting the glass fibres with natural fibres reduces the cost to RM400.

Minden Pulau Pinang

ID : tm3150412475


TYPHIDOT

Typhoid fever remains as a public health problem in many developing countries. There is a need for an alternative test for typhoid that is rapid, sensitive, specific and cost-effective. A novel approach to outer membrane studies by Prof Asma Ismail and her research team has paved the way for the discovery of 50kDa, a specific outer membrane protein for S. typhi. The specific protein was used to developed a rapid dot EIA test for typhoid called TYPHIDOTTM that detects for the presence of specific IgM and IgG to the 50 kD antigen. The test became a breakthrough in typhoid diagnosis since 1896 and could produce results within an hour compared to 2-5 days via the conventional culture method and 2 weeks via the serologiccal Widal test.

Minden Pulau Pinang

ID : tm3150512476


Tocotrienols

Tocotrienols belongs to the vitamin E family, which comprises 4 tocopherols and 4 tocotrienols. Unlike a-tocopherol, which is found more abundantly in nature, natural sources of tocotrianols are limited. They are not found in common vegetable oils such as peanut oil, sunflower oil, soybean oil and coconut oil. Hence little is known about the tocotrienols until rect

Minden Pulau Pinang

ID : tm3150612477


Thermoplastic prepregging system

The project aims to realize continuous Fibre TP Composites, woven and non woven by developing a local and indigenous prepregging system. With this system now, a wide range COFIT or simple prepregs that can be used to manufacture all sorts of thermoplastic based composites, suitable for different application.

Minden Pulau Pinang

ID : tm3150712478


STANEXTIB: Standardised Extract Based Bio-Enhancer for Anti TB Drug Isoniazid

Bio-enhancers synergize the activity of drugs by various mechanism and help in curing diseases,shortening the duration of treatment and improving patient quality of life.Despite many developments, TB is still more fatal among infectious diseases and a combination of drugs is recommended for a period of 3-9 months. With this in view, a natural bio-enhancer of isoniazid has been formulated and investigated for pre-clinical studies.STANEXTIB has shown the ability to enhance the activity of isoniazid to a level of 75%.The combination containing STANEXTIB and isoniazid (75% less) has shown activity equivalent to MIC of isoniazid 0.4??g/ml. Therefore,the concomitant use of STANEXTIB with isoniazid may improve drug compliance and reduce drug related side effects especially in long terms use of antibiotics.STANEXTIB has been prepared from a refined standarized extract of Piper sarmentosum. STANEXTIB has been evaluated for safety using animal models. STANEXTIB has been investigated using pharmacokinetic parameters involving absorption,distribution and excretion.The product has been evaluated for accelerated stability studied for the shelf life data. STANEXTIB is evidence based bio-enhancer of isoniazid ,an anti TB drug with complete pre clinical data for efficiancy, safety, bioavailability and stability and can be formulated in various dosage forms.

Minden Pulau Pinang

ID : tm3150812479


Standardized herbal Extract for Kidney Stone and Related Disease

Herbal standardization is to ensure guaranteed potency through acceptable levels of active compounds and carried out to ascertain consistency and repeatability of herbal material. This process is carried out chemically and biologically as a means of product quality assurance and currently is a leading edge technology where patents and commercialization's prospects are made possible

Minden Pulau Pinang

ID : tm3150912480


Standardized Extract of Formulated Misai Kucing (Orthosiphon Stamineus Benth)

Standardized Misai Kucing extract is the product of a multi-disciplinary research and development input from various areas of expertise ranging from Pharmacognosy, Phytochemistry and Pharma-ceutics. The main aim was to develop an extract with a standardized profile that guarantee its potency. Selection of quality dried leaves is based on gravimetric, microscopic, chromatographic and spectroscopic parameters and complies with standard data ofestablished techical monographs.

Minden Pulau Pinang

ID : tm3151012481


Standardized Eurycoma longifolia TAF 273 soft-gel capsule for the treatment of male infertility

Infertility in couples has been defined as the inability to conceive after more than a year of unprotected sexual intercourse and is amajor problem for those who are very keen to have children. While statistics from various sources might difertility affects 10% to 15% of couples where the male has contributed approximately 30% to 40% towards the problem. Male infertility can be due to lack of sperm in the semen, deformed or structurally abnormal sperm, sperms that lack the a ability to reach and fertilize a female egg, genetic disorders or an endocrice disorder.

Minden Pulau Pinang

ID : tm3151112482


Special Interest Goup Knowledge Portal (SIGKP)

Special Interest Group Knowledge Portal (SIGKP) serves as a generic framework to support the development of an online or electronic community (e-community) for technical special interest group (SIG) around the world. It applies a classification and visualization approach for knowledge management (KM-ClaVis) that enhances knowledge acquisition and knowledge sharing among an electronic e-community. SIGKP has been successfully applied to build the e-community for Malaysian Software Engineering Interest Group (MySEIG) available at www.myseig.org.

Minden Pulau Pinang

ID : tm3151212483


Solid Fermentation Process Using Agriculture Waste

Enzymes continue to play an important role in human life where a large number of processes utilises enzymes at some stage or another. Industries utilizing such processes include those in industrial, environmental and food biotechnology. Solid-state fermentation (SSF) holds tremendours potential for the production of enzymes as current developments in biotechnology are rapidly creating new application for enzymes. This invetion is a system for use in a solid-state fermentation process, comprising a fermenter module with plural ports that allows the ease of input of the required substrates and removal of the fermented products. At the same time, a control module is operatively inter-engaged with the fermenter module as a means of controlling the fermentation parameters.

Minden Pulau Pinang

ID : tm3151312484


SOFTWARE-BASE TELEPRESENCE SYSTEM

Telepresence refers to a set of technologies which allow a person to feel as if they were present, to give the appreance that they were present or to have an effect at a location other than their true location. The TelePresence system is baed on how High Definition video conferencing. This will allow participants from multiple locations to conduct meetings as if they were in the same meeting room, while actually hundreds or thounsands of kilometers separate them. Different from others, TelePresence system relay on software instead of hardware for video coding at the sending side and vidoe encoding at receiving side and yet able to achieve a very good quality TelePresence system by fullfiling the two basic requirements oof HD video and audio rea-time taransmission and maintaining a good quality of service and efficient storage, comprehension and decompression. This system is a green invention since it encourage more users to use it instead of fyling or driving to attend meetings or training. This will contribute towards reducinng users carbon footprint,which in turns will reduce Enviromental Impacts.

Minden Pulau Pinang

ID : tm3151412485


Secure Multimedia Conferencing System Over Wan

A secure delivery method for multimedia conferencing content through network.

Minden Pulau Pinang

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