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Wb rapid - An Immunochromatography test for the rapid and accurate detection of Wuchereria bancrofti filaria infection
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Lymphatic filariasis caused by Wuchereria bancrofti affects more than 100 million people in 80 countries. This mosquito-transmitted disease results in symptoms that include fever, lymphatic & renal damage, adenolymphangitis, hydrocoele, chyluria, lymphoedema and elephantiasis. Wb rapid is an immunochromatography-based rapid test for the detection of specific lgG to W. bancrofti. It employs BmSXP recombinant antigen which is immobilized on a membrane strip. If specific antibodies are present in the test sample (serum/plasma/blood), it forms an antibody-antigen complex with the immobilized antigen; and subsequently detection by a dye conjugated anti-human lgG, giving a pink-purplish coloured line/band. The control line contains goat anti-mouse lgG-dye conjugate, and serves as an indication of proper migration plus reagent control. The test demonstrated sensivity of 95-100% and specificity of 99-100%.

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Organization Name
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Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia
11800 Minden
Pulau Pinang
Malaysia

Full Name [1]
Prof. Rahmah Noordin
Email [1]
rahmahn@yahoo.com