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The Horseshoe Crab and their Use in Human Cardiac Disorders
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Marine natural products have always been a source of new leads for the treatment of many deadly diseases such as cancer,acquired immuno-deficiency syndrome (AIDS) etc. The pharmacology of marine compounds such as anti-helminthes,anti-bacterial,anti-coagulant,anti-diabetic,anti-fungal,anti-inflammatory,anti-malarial,anti-platelet,anti-protozoa,anti-tuberculosis anti-viral activities affecting the cardiovascular and nervous systems are highly encouraging.Several molecules isolated from various marine organism such as micro organisms,algae,fungi,invertebrates and vertebrates are currently under an advanced stage of clinical trials.Some of them have already been marketed as drugs.A number of marine peptides have been isolated in recent years which exhibit potent biological activities and many of the compounds showed promising anticancer activities. This present study thus opens up entirely new possibilities using peri-vitelline fluid of the horseshoe crab for medical application to improve stem cell differentiation into cardiomyocytes on severe ischemic diseases which cannot be improved by classic therapy.Though along Malaysian coast,three valuable species of the horseshoe crab are found but unfortunately not much work has been done on their bio-medical potential.Hence it is prudent o our part to put our sincere efforts to know more about the amazing creature.

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Institute of Tropical Aquaculture, Universiti Malaysia Terengganu, Mengabang Telipot
21030 Kuala Terengganu
Terengganu
Malaysia

Full Name [1]
Anil Chatterji
Email [1]
anilich_18@yahoo.co.in